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KMID : 0387919930040010041
Korean Journal of Cytopathology
1993 Volume.4 No. 1 p.41 ~ p.44
Cytologic Features of primary Amelanotic Melanoma of the Vagina



Abstract
A case of primary amelanotic melanoma of the vagina diagnosed in scraping smear is described A 64-year-old woman complained of vaginal bleeding with a 2.5¡¿2cm sized, fungating mass on the right lateral vaginal wall near the introitus
for
2
months.
Scraping smears from the mass showed scattered individual tumor cells with single, bi- or multi-nucleated eccentric nuclei having prominent macronucleoli and occasional intranuclear inclusions. The cytoplasm was plump and cyanophilic
with a
indistinct rim. No melanin pigment was identified.
Characteristic cytologic features of this case were very helpful to exclude more common squamous cell carcinoma in the vagina, which was strongly suggested in biopsy specimen.
KEYWORD
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